Macrophages reside within essentially every tissue of the body and act as sentinels. Macrophages are key members of the innate immune system that perform many important tasks including antigen presentation, clearance of pathogens and apoptotic cells, and promotion of tissue repair and regeneration.
Using Flow Cytometry to Identify Distinct Macrophage Populations Within the Murine Liver As always, you will receive the highest quality histology in the quickest turn-around time.ĭid you know the more samples you submit to the histology lab the less you pay per sample? Contact Lori to find out how! Contact Lori at the McGowan Core Histology Lab and ask about our staining specials. Through the month of July you will receive 30% off your Safranin O Staining, when you mention this ad. The cartilage and mucin will be stained orange to red, and the nuclei will be stained black. Safranin O Staining is used for the detection of cartilage, mucin, and mast cell granules on formalin-fixed, paraffin-embedded tissue sections, and may be used for frozen sections as well.
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Regenerative Medicine techniques are being developed to generate new cartilage, using cell plus “scaffold” materials to grow replacement cartilage.
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In recent years, surgeons and scientists have developed a series of cartilage repair procedures that help to postpone the need for joint replacement. RESOURCES AT THE MCGOWAN INSTITUTE July Special at the Histology Lab The integrity of the cells and vital metabolic activity is sustained for eventual transplantation of the organ.” “In our new system, we pump a special fluid designed to deliver oxygen to the liver, creating an environment that supports normal function. “Standard practice is to use a method called cold static preservation, which uses tissue cooling to slow down metabolism with the aim of reducing the demand for oxygen and thus protecting cells from death,” Dr. If the damage is too extensive, the organ cannot be safely transplanted into a patient. Listen to the interview here.Ĭurrently, 20 to 40 percent of donor livers cannot be transplanted into recipients because oxygen deprivation during storage and transport in conventional containers can make pre-existing tissue damage worse, explains Dr. Rankings are based on the potential positive impact the submitted technology will have on a specific industry sector. The TechConnect Innovation Awards selects the top early-stage innovations from around the world through an industry-review process of the top 15% of annually submitted technologies into the TechConnect National Innovation Summit. Fontes, was also selected as a 2016 TechConnect Innovation Awardee. Fontes received his award from Chancellor Patrick Gallagher, Provost Patricia Beeson, and Senior Vice Chancellor for the Health Sciences and Dean of the School of Medicine, Arthur Levine (all pictured with Dr. It creates a new technology for organ and tissue preservation based on the combined use of machine perfusion and a new hemoglobin-based oxygen carrier solution. This project was originally sponsored by a charitable fund from the Virginia Garcia de Souza (VGS) Foundation, Sao Paulo, SP, Brazil.
McGowan Institute for Regenerative Medicine deputy director Paulo Fontes, MD, FACS, UPMC transplant surgeon and associate professor, Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh School of Medicine, received a 2016 Pitt Innovator Award for his scientific discovery, which has been patented (WO2014059316 A1, PCT/US2013/064607) and further licensed by VirTech Bio LLC, Beverly, Massachusetts. The University of Pittsburgh has witnessed more than 120 startup companies launched based on Pitt-developed inventions since 1996. 6| Research Discovery Receives Accolades and Recognition
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